Dr. Robert Schneider (2005 - 2008)

++49 - 551 - 201 2211 e-mail Max-Planck-Institut für Biophysikalische Chemie Dept. for NMR-based Structural Biology Solid-State NMR Am Fassberg 11 37077 Göttingen Germany

• Protein structure and dynamics
• Solid state NMR spectroscopy
• Protein folding
• Computer simulations of biomolecules

PCGG activities

Cooperation(s):

• Rice - Suhm group (FTIR spectroscopy of polyamino acids)
• Steisel - Buback group (Solid State NMR of ethylene copolymers)
• Nguyen - Vana group (Solid State NMR of RAFT agents on silica)
• Zachariae - de Groot group (Molecular dynamics studies of toxin binding to a potassium channel)

• Project Week in the de Groot Group: Setting Up a Molecular Dynamics Simulation Box of a Membrane Protein

• ♦ R. Schneider, M. Etzkorn, K. Giller, V. Daebel, J. Eisfeld, M. Zweckstetter, C. Griesinger, S. Becker, A. Lange, The Native Conformation of the Human VDAC1 N Terminus, Angew Chem Int Ed Engl 2010, 49, 1882-1885.
• ♦ C. Ader, R. Schneider, K. Seidel, M. Etzkorn, S. Becker, M. Baldus, Structural rearrangements of membrane proteins probed by water-edited solid-state NMR spectroscopy, J. Am. Chem. Soc., (in press 2008). (Advance online publication)
• ♦ O. Pongs, C. Ader, R. Schneider, S. Hornig, P. Velisetty, E. M. Wilson, A. Lange, K. Giller, M. F. Martin-Eauclaire, D. Trauner, S. Becker, M. Baldus, A structural link between potassium channel gating and drug binding, FEBS J 2008, 275, 174-174.
• ♦ R. Schneider, C. Ader, A. Lange, K. Giller, S. Hornig, O. Pongs, S. Becker, M. Baldus, Solid-state NMR spectroscopy applied to a chimeric potassium channel in lipid bilayers, J. Amer. Chem. Soc. 2008, 130, 7427-7435.
• ♦ C. Ader*, R. Schneider*, S. Hornig, P. Velisetty, E. M. Wilson, A. Lange, K. Giller, I. Ohmert, M. F. Martin-Eauclaire, D. Trauner, S. Becker, O. Pongs, M. Baldus, A Structural Link between Inactivation and Block of a K+ channel, Nature Struct. Mol. Biol. 2008, 15, 605-612. ( * equally contributing authors)
• ♦ J. Korukottu, R. Schneider, A. Lange, V. Vijayan, O. Pongs, S. Becker, M. Baldus, M. Zweckstetter, High-resolution 3D structure determination of kaliotoxin by solid-state NMR spectroscopy, PLoS ONE 2008, 3 (6), e2359.
• ♦ U. Zachariae, R. Schneider, P. Velisetty, A. Lange, D. Seeliger, S. J. Wacker, Y. Karimi-Nejad, G. Vriend, S. Becker, O. Pongs, M. Baldus, B. L. de Groot, The molecular mechanism of toxin-induced conformational changes in a potassium channel: relation to C-type activation, Structure 2008, 16, 747-754.
• ♦ C. Ader, R. Schneider, K. Seidel, M. Etzkorn, M. Baldus, Magic-Angle-Spinning NMR spectroscopy applied to small molecules and peptides in lipid bilayers, Biochem. Soc. Trans. 2007, 35, 991-5.
• ♦ R. Schneider, M. Riesenhuber, On the difficulty of feature-based attentional modulations in visual object recognition: A modeling study., AI Memo 2004-004, CBCL Memo 235, MIT AI Lab and CBCL, Cambridge, MA 2004, , .
  [ Link: http://www.ai.mit.edu/publications/ ]
• ♦ R. Schneider, M. Riesenhuber, A detailed look at scale and translation invariance in a hierarchical neural model of visual object recognition, AI Memo 2002-011, CBCL Memo 218, MIT AI Lab and CBCL, Cambridge, MA 2002, , .
  [ Link: http://www.ai.mit.edu/publications/ ]

• Talk: Sept 23 2008 A structural link between inactivation and block of a K+ channel (Annual Discussion Meeting of the Magnetic Resonance Spectroscopy Division of the German Chemical Society (GDCh), Regensburg)
• Poster: April 07 2008 Studying Potassium Channel Structure and Inactivation in Lipid Bilayers by Solid-State NMR (11th Workshop)
• Talk: April 07 2008 Studying Potassium Channel Structure and Inactivation in Lipid Bilayers by Solid-State NMR (11th Workshop)
• Poster: Mar 10 2008 Studying Potassium Channel Structure and Inactivation in Lipid Bilayers by Solid-state NMR (49th Experimental NMR Conference (ENC) 2008, Pacific Grove, CA, USA)
• Talk: Sept 17 2007 Solid-state NMR spectroscopy applied to the full-length KcsA-Kv1.3 potassium channel in lipid bilayers (10th Workshop)
• Organization: Sept 17 2007 Co-organization of 10th workshop (10th Workshop)
• Talk: Sept 11 2007 Solid-state NMR spectroscopy applied to the full-length KcsA-Kv1.3 potassium channel in lipid bilayers (Alpine Conference on Solid-State NMR, Chamonix, 2007)
• Poster: Mar 20 2007 Molecular motion detected by double-quantum (¹³C,¹³C) solid-state NMR (9th Workshop)
• Organization: Mar 19 2007 Chairman at the 9th Workshop, Marseille
• Organization: Dec 20 2006 Host student of U. Hensen
• Talk: Oct 09 2006 Structure and dynamics of peptides and proteins investigated by solid-state NMR (Eighth Workshop 2006)
• Organization: Oct 08 2006 Coordination of 8th workshop (Eighth Workshop 2006)
• Poster: Aug 20 2006 Chemical-shift variations correlate with structural differences in microcrystalline ubiquitin (ICMRBS, Göttingen, August 20-25, 2006)
• Poster: Jul 16 2006 Chemical-shift variations correlate with structural differences in microcrystalline ubiquitin (EUROMAR, York, England, July 16-21, 2006)
• Participation: May 29 2006 European School on Solid State NMR, Advanced Level Course in Biological Solids (Brückentinsee, Germany, May 29th to June 2nd, 2006)
• Talk: April 24 2006 Solid-state NMR: Principles and applications to proteins and polymers (Group seminar (Samwer Group) , First Physical Institute, University of Göttingen)
• Poster: Mar 21 2006 Structural studies on polymers, peptides and proteins using solid-state NMR (Review Colloquium)
• Organization: Mar 09 2006 Student evening at the 7th Workshop (Seventh Workshop 2006
  Spectroscopy and Dynamics of Molecular Coils and Aggregates (Göttingen - Paris))
• Organization: Mar 09 2006 Host student of A. Böckmann (Seventh Workshop 2006
  Spectroscopy and Dynamics of Molecular Coils and Aggregates (Göttingen - Paris))
• Poster: Mar 08 2006 Structural studies on polymers, peptides and proteins using solid-state NMR (Seventh Workshop 2006
  Spectroscopy and Dynamics of Molecular Coils and Aggregates (Göttingen - Paris))
• Talk: Feb 20 2006 Structural studies on ubiquitin using solid-state NMR (Group seminar, NMR II department, Max-Planck-Institute for Biophysical Chemistry)
• Poster: Sept 27 2005 Refinement of MAS-based molecular structures using chemical-shift selective transfer methods (High-Field Bio-NMR Symposium of the GDCh Magnetic Resonance Division, Mainz)
• Organization: Sept 06 2005 Student speaker of the graduate school since Sept 2005
• Talk: Sept 05 2005 Probing structure and dynamics of biomolecules by solid-state NMR (Sixth Workshop 2005)